The Order of Saint Constantine supports the following charities:
- Hospices of Hope: Runs hospices that provide palliative care in southeastern Europe
- Interfaith Coalition: Provides shelter and support for the homeless of Whatcom County, Washington
- Marie Curie: Provides palliative care and support for the terminally ill in the United Kingdom
- Medecins Sans Frontieres: Delivers emergency medical aid worldwide
- Oxfam: Provides food, clean water, and healthcare to people around the world
- Samaritan's Purse: Provides food, water, shelter and medicine to those hit by disasters, and helps churches to evangelise
- St Raphael's Hospice: Provides palliative care and support for the terminally ill in Sutton and Merton, England
- WaterAid: Provides safe water and sanitation to people around the world
- World Food Programme: Provides food to the hungry around the world